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Writer's pictureAlan Sun

The Revolutionary Endosymbiotic Theory: Exploring the Origins of Eukaryotic Cells

Embarking on a journey through the microscopic realms of life, the revolutionary Endosymbiotic Theory unveils a narrative that challenges conventional wisdom about the origins of complex cells. Picture the biological landscape over a billion years ago, where simple single-celled organisms ruled the primordial seas. The story begins with a symbiotic dance between different microorganisms, an intricate interplay that laid the groundwork for the emergence of eukaryotic cells—the building blocks of all complex life.


The endosymbiotic theory posits that certain organelles found in contemporary eukaryotic cells were originally independent prokaryotic microbes. According to this theory, the initial eukaryotic cell resembled an amoeba-like entity, obtaining nutrients through phagocytosis and featuring a nucleus that materialized when a portion of the cytoplasmic membrane enclosed the chromosomes. Within this context, amoeba-like organisms engaged in the ingestion of prokaryotic cells, giving rise to a symbiotic relationship. The ingestion of bacteria proficient in aerobic respiration led to the formation of mitochondria, while the incorporation of photosynthetic bacteria resulted in the creation of chloroplasts.



As these organelles established residence within the host cell, they underwent transformative changes, shedding their cell walls and relinquishing much of their DNA. This evolution was driven by the diminished utility of these attributes within the confines of the host cell. Notably, mitochondria and chloroplasts, having become integral components of the host cell, lost the ability to grow independently outside of their cellular abode.


This captivating narrative challenges traditional notions of cellular evolution, painting a picture of intricate relationships and transformative partnerships that have sculpted the complexity of eukaryotic cells. The endosymbiotic theory not only reshapes our understanding of the origins of cellular structures but also underscores the dynamic and interconnected nature of life's evolutionary journey.


Evidence to support the endosymbiotic theory include:

  • Chloroplasts and mitochondria have the same size as prokaryotic cells and divide by binary fission

  • Mitochondria and chloroplasts have their own DNA that is circular, not linear

  • Mitochondria and chloroplasts have their own ribosomes that are 70s, not 80s.



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